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How does pep 14 work?

The underlying mechanism of action is likely via the modulation of a subunit of PP2A, a lesser explored target in the longevity field. When used in 2D and 3D aged skin models, Pep 14 promoted tissue rejuvenation.

What is pepfect 14?

Here, we describe a new stearylated CPP that we designate PepFect 14 (PF14). It is a modified version of our previously reported peptide, stearyl-transportan10 (stearyl-TP10) ( 21 ), where we utilized ornithines and leucines instead of lysines and isoleucines.

How is Pep 14 treated?

Treatments were performed by adding the molecule in the culture media or with a topical formulation. In 3D skin equivalent assays, Pep 14 was used at 1 μM, and Rapamycin at 100 nM. Treatment was added to the culture media on day 0 and day 3. Topical Pep 14 treatment consisted of 0.01% Pep 14 in a 15% oil moisturizing emulsion.

Die weltweit führende Krypto-Handelsplattform

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